5:30 PM - 6:00 pm

RECEPTION

Refreshments & Networking

• HOSTED BY: EDGEWISE THERAPEUTICS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

• VIRTUAL: *NOT AVAILABLE*

6:00 PM - 7:00 PM

SPONSOR PRODUCT THEATER: Evolving Paradigms for the Treatment of HCM: Unmet Needs and Emerging Therapeutic Approaches

• HOSTED BY: EDGEWISE THERAPEUTICS

• OVERVIEW / SPEAKERS / RSVP

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

• VIRTUAL: *NOT AVAILABLE*

7:00 PM - 8:00 PM

PAs & NPs of HCM: A Networking Night

• OVERVIEW & RSVP

• Co-HOSTED BY: Anna Rodonski, PA-C & Catherine Carroll, NP

• IN-pERSON: Flagship BALLROOM / MEZZANINE LEVEL 2

• VIRTUAL: *NOT AVAILABLE*

7:30 AM - 8:30 AM

EXHIBITS & BREAKFAST

-INTRODUCTION & GENETICS-

8:30 AM

Welcome

Martin S. Maron, MD & Steve R. Ommen, MD

8:35 AM

HCM At 65 Years: A Contemporary Treatable Disease. How Did This Happen?

Barry J. Maron, MD

8:55 AM

How Common is HCM Really?

Daniele Massera, MD, MSc

9:10 AM

The Max Saines Lecture: Familial & Nonfamilial Inheritance: Is HCM Always Genetic?

Jodie Ingles, MPH, PhD

9:35 AM

Why Should I Get Genetic Testing on My HCM Patient?

Anjali T. Owens, MD

9:55 AM

BREAK

10:10 AM

Gene (+) / Phenotype (-): Is There Anything to Do (Yet)?

Michelle Michels, MD, PhD

10:30 AM

Novel Views on HCM Screening from a Pediatric Perspective

Seema Mital, MD, FRCP

10:50 AM

PANEL DISCUSSION: Prevalence, Genetics, Screening

Drs. Ingels, Massera, Michels, Mital, Owens

Steve R. Ommen, MD (Moderator)

-IMAGING-

11:15 AM

Cardiac Magnetic Resonance In HCM: LGE, ESV & What the HCMR Registry May Tell Us

Milind Desai, MD, MBA

11:35 AM

Integrating Echocardiography & Multimodality Imaging to Improve Contemporary HCM Care

Harry Rakowski, MD, FRCPC

12:00 PM

LUNCH

12:05 PM

SPONSOR PRODUCT THEATER: A Contemporary Case-Based Discussion of Cardiac Myosin Inhibition for the Management of NYHA Class II-III Symptomatic Obstructive HCM Patients

• Hosted By: BRISTOL MYERS SQUIBB

• OVERVIEW & SPEAKERS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

• ON-DEMAND: *NOT AVAILABLE*

1:10 PM

Improving Diagnosis & Beyond In HCM: Will Artificial Intelligence Be the Answer?

Konstantinos Siontis, MD

1:30 PM

PANEL DISCUSSION: Modern Imaging & Management of HCM

Drs. Desai, Rakowski, Saberi, Siontis

Martin S. Maron, MD (Moderator)

1:55 PM

BREAK

-PREVENTION OF SUDDEN DEATH-

2:10 PM

Risk Stratification to Save Lives: Selection of Patients for ICD

Martin S. Maron, MD

2:35 PM

Unique Challenges in Sudden Death Prevention in Young HCM Patients: Aren’t Kids Just Small Adults?

Gabrielle Norrish, BMBCh, PhD

3:00 PM

Selection of Devices to Prevent Sudden Death: Sub-Q v. Transvenous ICD?

Danna A. Spears, MD

3:20 PM

PANEL DISCUSSION: Risk Stratification

Drs. M. Maron, Michels, Norrish, Spears

Barry J. Maron, MD (Moderator)

3:45 PM

Differential Diagnosis: Diseases That Look Like HCM But Are Not: Identification & Precision Medicine Strategies

Danon Disease - Eric D. Adler, MD

Cardiac Amyloidosis - Mat Maurer, MD

Fabry Disease - Albree Tower-Rader, MD

Group Q&A - Martin Maron, MD (Moderator)

4:45 PM

ADJOURN

5:00 PM

SPONSOR PRODUCT THEATER: Unlocking the Diagnostic and Prognostic Mysteries of Fabry Disease and the Role of cMRI 

• Hosted By: SANOFI

• OVERVIEW & SPEAKERS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

• VIRTUAL: *NOT AVAILABLE*

6:00 PM - 8:00 PM

RECEPTION

Cocktails & Hors d’oeuvres for In-Person Registrants, Faculty & Industry

• SPONSORED BY: CYTOKINETICS

• IN-pERSON: LIGHTHOUSE BALLROOM / PLAZA LEVEL 3

• VIRTUAL: *NOT AVAILABLE*

7:00 AM - 8:30 AM

EXHIBITS & BREAKFAST

7:15 AM - 8:15 AM

SPONSOR PRODUCT THEATER: Updates in Cardiac Ambulatory Monitoring for HCM Management: A Case-Based Discussion

• Hosted By: ZIO BY IRHYTHM

• OVERVIEW & SPEAKERS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

-HEART FAILURE IN OBSTRUCTIVE HCM-

8:30 AM

Obstructive HCM: Recognition, Mechanism, Natural History

Steve R. Ommen, MD

8:55 AM

Traditional Medical Therapies with Beta-Blocker/Calcium Channel Blockers (and Don’t Forget about Disopyramide)

Mark V. Sherrid, MD

9:15 AM

From Bench to Bedside: The Incredible Story Behind the Development of Myosin Inhibitors

Fady I. Malik, MD, PhD

9:35 AM

BREAK

9:50 AM

First Generation Cardiac Myosin Inhibitor: What Have We Learned & Where Are We Going?

Iacopo Olivotto, MD

10:15 AM

Next-In-Class Myosin Inhibitor: What Can We Expect?

Martin S. Maron, MD

10:40 AM

What Is the Evidence for Cardiac Remodeling with Myosin Inhibitors…And Is It Different Than with Septal Reduction Therapies?

Andrew Wang, MD

11:00 AM

Integrating Myosin Inhibitors into Busy Cardiovascular Practices: Practical Insights

Theodore Abraham, MD

11:15 AM

PANEL DISCUSSION: Deeper Dive into Novel Drug Therapy

Drs. Abraham, M. Maron, Olivotto, Sherrid, Wang

Steve R. Ommen, MD (Moderator)

11:40 AM

LUNCH

11:45 AM

SPONSOR PRODUCT THEATER: Clinical Meaningfulness of pVO2: Does It Matter in HCM?

• Hosted By: CYTOKINETICS

• OVERVIEW & SPEAKERS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

12:50 PM

The Doug Wigle Lecture: Surgical Septal Myectomy: The Gold Standard. Should We Be Operating Earlier?

Joseph Dearani, MD

1:10 PM

Operating on Obstructive HCM with Mild Septal Hypertrophy: Expanding the Myectomy Spectrum

Prem Shekar, MD

1:25 PM

How Do We Develop More Great Myectomy Surgeons?

Eduard Quintana, MD, PhD

1:40 PM

Alcohol Septal Ablation: 30 Years Later

Rick A. Nishimura, MD

2:00 PM

Future of Catheter-Based Therapies for Obstructive HCM

Carey Kimmelstiel, MD

2:20 PM

Contemporary Management of Obstructive HCM: Putting It All Together in the Era of Novel Drug Therapies

Steve R. Ommen, MD

2:40 pm

PANEL DISCUSSION: Management of Outflow Tract Obstruction

Drs. Dearani, Kimmelstiel, Nishimura, Quintana, Shekar

Martin Maron, MD (Moderator)

3:05 PM

BREAK

-HEART FAILURE IN NON-OBSTRUCTIVE HCM-

3:20 PM

Non-Obstructive HCM: Recognition, Mechanism, Natural History & Mortality

Ethan J. Rowin, MD

3:40 PM

Current Management of End-Stage Heart Failure with or without Systolic Dysfunction: Drugs, Devices & Who Should Be Listed for Heart Transplant?

Michelle Kittleson, MD, PhD

4:00 PM

Is More Help on The Way? Future Medical Therapies for Nonobstructive HCM

Ahmad Masri, MD, MS

4:20 PM

Atrial Fibrillation: Unique Perspectives on Management

Ethan J. Rowin, MD

4:40 pm

PANEL DISCUSSION: Heart Failure in Non-Obstructive HCM

Drs. Kittleston, Masri, Rowin, Dearani

Martin S. Maron, MD (Moderator)

4:55 PM

ADJOURN

5:15 PM-6:15 PM

SPONSOR PRODUCT THEATER: From Algorithms to Outcomes: AI's Promise and Potential Pitfalls

• Hosted By: VIZ.AI

• OVERVIEW & SPEAKERS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

6:30 PM

RECEPTION: HCMA Patient Perspective & Voice

Cocktails & Light Dinner for All Registrants, Faculty & Industry with special programming from the HCMA.

• HOSTED BY: THE HCMA & LISA SALBERG

• IN-pERSON: LIGHTHOUSE BALLROOM / PLAZA LEVEL 3

• VIRTUAL: *NOT AVAILABLE*

• RSVP: Please use the blue button below

6:45 AM - 8:15 AM

BREAKFAST

7:00 AM - 8:00 AM

SPONSOR PRODUCT THEATER: Meet The Experts: Tenaya Therapeutics Talks About Their Efforts to Bring TN-201 Gene Therapy for HCM to Patients

• HOSTED BY: TENAYA THERAPEUTICS

• OVERVIEW / SPEAKERS

• IN-pERSON: SEAPORT BALLROOM / MEZZANINE LEVEL 2

-ELEVATING HCM CARE-

8:15 AM

Different Outcomes by Race?: Improving HCM Care for Minorities

Melissa S. Burroughs, MD, MS

8:25 AM

Delivering Optimal Care in HCM: The Role of Advanced Practitioners

Deatrah DuBose, ACNP, BC

-THE FUTURE OF CLINICAL TRIALS IN HCM-

8:35 AM

The Enormous Challenge of End Points: Will New HCM Therapies Live or Die by This Issue?

James Udelson, MD

8:50 AM

How Exactly Are Drugs Approved? Drug Approval in Rare Diseases: The View of the FDA

Rosalyn Adigun, MD

9:05 AM

PANEL DISCUSSION: HCM Clinical Trial Design

Drs. Adigun, Burroughs, Udelson; Ms. Salberg

Steve R. Ommen, MD (Moderator)

-EXERCISE IN ATHLETES-

9:20 AM

Exercise In HCM: What Should We Be Telling Patients?

Rachel Lampert, MD

9:30 AM

Exercise in HCM: Why Don’t We Just Let Them All Play?

Matthew W. Martinez, MD

9:40 AM

Decision-Making For Sports Eligibility in HCM: Efforts to Keep the Patients & Athletic Field Safe

Barry J. Maron, MD

9:50 AM

PANEL DISCUSSION: Exercise in HCM

Drs. Lampert, B. Maron, Martinez

Martin S. Maron, MD (Moderator)

10:15 AM

BREAK

-GLOBAL EXPERIENCE OF HCM-

10:30 AM

Myectomy in a War Zone: The Ukrainian Surgical Experience

Kostiantyn Rudenko, MD, PhD

10:45 AM

China: Global Expanse of HCM & Myectomy

Shuiyun Wang, MD

11:00 AM

Decoding 500 Years of HCM: What Iceland Has Taught Us & What More We May Learn

Berglind Adalsteinsdottir, MD, PhD

11:15 AM

India: Trials & Tribulations of Growing an HCM Center In the World’s Most Populous Country

Hisham Ahamed, MD, DM

11:30 AM

HCM in Africa

Ntobeko Ntusi, MD, MBChB

11:45 AM

BREAK

-GENE THERAPY: IS IT FINALLY HERE?-

12:00 PM

Gene Therapy: Editing, Precision, Personalized Medicine…What Does It All Mean for HCM & Why?

Eric D. Adler, MD

12:20 PM

Status of Gene Therapy Clinical Trials In HCM & What To Expect Moving Forward

Louisa Mestroni, MD, FACC

12:40 PM

EPILOGUE: What the Past May Teach Us About the Future

Martin S. Maron, MD

12:45 PM

ADJOURN